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Harrison's Principles of Internal Medicine, 18e
Part 11. Disorders of the Respiratory System > Section 2. Diseases of the Respiratory System >
Chronic Obstructive Pulmonary Disease: Introduction
Topics Discussed:
chronic obstructive pulmonary disease.
Excerpt:
"
Chronic obstructive pulmonary disease (COPD) is defined as a disease state characterized by airflow limitation that is not fully reversible (
http://www.goldcopd.com/
). COPD includes
emphysema
, an anatomically defined condition characterized by destruction and enlargement of the lung alveoli;
chronic bronchitis
, a clinically defined condition with chronic cough and phlegm; and
small airways disease
, a condition in which small bronchioles are narrowed. COPD is present only if chronic airflow obstruction occurs; chronic bronchitis
without
chronic airflow obstruction is
not
included within COPD...."
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