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Fitzpatrick's Dermatology in General Medicine, 7e | Part 1. Introduction > Section 3: Overview of Biology, Development, and Structure of Skin > | Chapter 7. Development and Structure of Skin Sections: Skin: An Overview, Epidermis, Dermal-Epidermal Junction, Dermis, Cutaneous Vasculature, Cutaneous Nerves and Receptors, Hypodermis (Subcutis), Development of Skin, Development of Skin Appendages, References. Topics Discussed: skin.
Excerpt:
"Skin is a complex organ that protects its host from its environment,
at the same time allowing interaction with the environment. It is
much more than a static, impenetrable shield against external insults.
Rather, the skin is a dynamic, complex, integrated arrangement of
cells, tissues, and matrix elements that mediates a diverse array
of functions: skin provides a physical permeability barrier, protection
from infectious agents, thermoregulation, sensation, ultraviolet
(UV) protection, wound repair and regeneration, and outward physical
appearance (Table 7-1). These various functions
of skin are mediated by one or more of its major regionsthe
epidermis, dermis, and hypodermis (Fig. 7-1;
see also Fig. 6-1, Chap. 6). These divisions are interdependent, functional units; each
region of skin relies upon and is connected with its surrounding
tissue for regulation and modulation of normal structure and function at
molecular, cellular, and tissue levels of organization (see Chap. 6)...."
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