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Fitzpatrick's Dermatology in General Medicine, 7e
| Part 2. Disorders Presenting in Skin and Mucous Membranes > Section 8. Disorders of Epidermal and Dermal-Epidermal Cohesion and Vesicular and Bullous Disorders > |
Chapter 59. Dermatitis Herpetiformis
Sections: Epidemiology,  History, Etiology and Pathogenesis, Clinical Manifestations, Laboratory Tests, Associated Problems, Differential Diagnosis, Treatment, References.
Topics Discussed: dermatitis herpetiformis.
Excerpt:
"
Dermatitis herpetiformis (DH) is characterized
by an intensely itchy, chronic papulovesicular eruption that usually
is distributed symmetrically on extensor surfaces. The disease can
be clearly distinguished from the other sub-epidermal blistering
eruptions by histologic, immunologic, and gastrointestinal criteria.
The prevalence of DH in various Caucasian populations varies between 10
and 39/100,000 persons.1–3 It
may start at any age, including childhood; however, the second,
third, and fourth decades are the most common. After presentation,
DH persists indefinitely, although with varying severity. Patients
with DH have an associated gluten-sensitive enteropathy (GSE) that
is usually asymptomatic...."
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