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Quick Medical Diagnosis & Treatment
Hyperglycemic Hyperosmolar State
Sections: Key Features, Essentials of Diagnosis, General Considerations, Demographics, Clinical Findings, Symptoms and Signs, Differential Diagnosis, Diagnosis, Laboratory Tests, Treatment, Medications, Fluid Replacement, Insulin, Potassium, Phosphate, Therapeutic Procedures, Outcome, Complications, Prognosis, When to Admit, References,
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Topics Discussed: hyperglycemia hyperosmolar.
Excerpt: | |  Fluid replacement paramount to correct fluid deficits of 6–10 L
In hypovolemic oliguric hypotension, initiate fluid resuscitation with isotonic 0.9% saline Otherwise, hypotonic (0.45%) saline preferred because of hyperosmolality As much as 4–6 L of fluid may be required in first 8–10 h Once blood glucose reaches 250 mg/dL (13.9 mmol/L), add 5% dextrose to either water, 0.45% saline solution, or 0.9% saline solution at a rate to maintain serum glucose levels of 250–300 mg/dL (13.9 to 16.7 mmol/L) to reduce risk of cerebral edema Goal of fluid therapy is to restore urinary output to  50 mL/h |
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