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Quick Medical Diagnosis & Treatment Hypopituitarism Sections: Key Features, Essentials of Diagnosis, General Considerations, Clinical Findings, Symptoms and Signs, Differential Diagnosis, Diagnosis, Laboratory Tests, Imaging Studies, Treatment, Medications, Secondary adrenal insufficiency, Hypothyroidism, Hypogonadism, GH deficiency, Hyperprolactinemia, Surgery, Therapeutic Procedures, Outcome, Follow-Up, Complications, Prognosis, Prevention, References,
. Topics Discussed: hypopituitarism. Excerpt: | | Hydrocortisone tablets, 1535 mg/d orally in divided doses, should be given
Most patients do well with 1020 mg in the morning and 515 mg in the late afternoon
Partial ACTH deficiency (basal morning serum cortisol > 8 mg/dL [220 mmol/L]) requires hydrocortisone maintenance doses of ~5 mg twice daily orally
Some patients feel better with equivalent doses of prednisone 3.07.5 mg/d
Monitor patients for manifestations of Cushing syndrome or underreplacement. A serum WBC is useful, because a relative neutrophilia and lymphopenia can indicate overreplacement with corticosteroid, and vice versa
Give additional hydrocortisone during stress
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