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Quick Medical Diagnosis & Treatment
Syndrome of Inappropriate Antidiuretic Hormone (SIADH)
Sections: Key Features, Essentials of Diagnosis, General Considerations, Clinical Findings, Symptoms and Signs, Diagnosis, Laboratory Tests, Treatment, Medications, Symptomatic hyponatremia, Asymptomatic hyponatremia, Outcome, Follow-Up, Complications, Prognosis, When to Admit, References,
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Topics Discussed: inappropriate adh syndrome.
Excerpt: | |  Initial goal: Achieve serum sodium concentration of 125–130 mEq/L, guarding against overly rapid correction
Increase serum sodium concentration by  1–2 mEq/L/h and not > 25–30 mEq/L in first 2 days to prevent cerebral osmotic demyelination Rate should be reduced to 0.5–1.0 mEq/L/h as neurologic symptoms improve With CNS symptoms, hyponatremia should be immediately treated at any level of serum sodium concentration | | – Hypertonic (eg, 3%) saline plus furosemide (0.5–1.0 mg/kg intravenously) indicated for symptomatic hyponatremia – To determine how much 3% saline (513 mEq/L) to administer, obtain a spot urinary Na+ after a furosemide diuresis has begun
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