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Harper's Illustrated Biochemistry, 29e Chapter 4. Proteins: Determination of Primary Structure Sections: Objectives, Biomedical Importance, Proteins & Peptides Must Be Purified Prior to Analysis, Sanger Was the First to Determine the Sequence of a Polypeptide, The Edman Reaction Enables Peptides & Proteins to Be Sequenced, Molecular Biology Revolutionized the Determination of Primary Structure, Genomics Enables Proteins to Be Identified from Small Amounts of Sequence Data, Mass Spectrometry Can Detect Covalent Modifications, Mass Spectrometers Come in Various Configurations, Proteomics & the Proteome, Summary, References. Topics Discussed: amino acids and peptides; amino acids and proteins; protein structure; proteins; proteins: structure and function. Excerpt:"After studying this chapter, you should be able to:..."
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