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Harper's Illustrated Biochemistry, 29e Chapter 23. Biosynthesis of Fatty Acids & Eicosanoids Sections: Objectives, Biomedical Importance, The Main Pathway for De Novo Synthesis of Fatty Acids (Lipogenesis) Occurs in the Cytosol, The Nutritional State Regulates Lipogenesis, Short- & Long-Term Mechanisms Regulate Lipogenesis, Some Polyunsaturated Fatty Acids Cannot Be Synthesized by Mammals & Are Nutritionally Essential, Monounsaturated Fatty Acids Are Synthesized by a 9 Desaturase System, Synthesis of Polyunsaturated Fatty Acids Involves Desaturase & Elongase Enzyme Systems, Deficiency Symptoms Are Produced When the Essential Fatty Acids (EFA) Are Absent from the Diet, Eicosanoids Are Formed from C20 Polyunsaturated Fatty Acids, The Cyclooxygenase Pathway Is Responsible for Prostanoid Synthesis, Leukotrienes & Lipoxins Are Formed by the Lipoxygenase Pathway, Clinical Aspects, Summary, References. Topics Discussed: biosynthesis of fatty acids and eicosanoids; eicosanoid biosynthesis; fatty acid biosynthesis. Excerpt:"After studying this chapter, you should be able to:..."
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