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Harper's Illustrated Biochemistry, 29e
Chapter 55. Cancer: An Overview
Sections: Objectives, Biomedical Importance, Some General Comments on Neoplasms, Fundamental Features of Carcinogenesis, Causes of Genetic Damage, Radiant Energy, Chemicals, and Certain Viruses Are the Major Known Causes of Cancer, Oncogenes and Tumor Suppressor Genes Play Key Roles in Causing Cancer, Growth Factors & Abnormalities of Their Receptors and Signaling Pathways Play Major Roles in Cancer Development, Many Cancers Can Be Prevented by Modifying Risk Factors, Abnormalities of the Cell Cycle Are Ubiquitous in Cancer Cells, Genomic Instability and Aneuploidy Are Important Characteristics of Cancer Cells, Many Cancer Cells Display Elevated Levels of Telomerase Activity, A Number of Cancers Have a Hereditary Predisposition, Whole Genome Sequencing of Tumor Cells Is Providing New Insights Regarding Cancer, Cancer Cells Have Abnormalities of Apoptosis that Prolong Their Lives, Epigenetic Mechanisms Are Involved in Cancer, There Is Much Interest in the Role of Stem Cells in Cancer, Tumors Often Stimulate Angiogenesis, Metastasis Is the Most Serious Aspect of Cancer, Cancer Cells Exhibit a High Rate of Aerobic Glycolysis, Mitochondria Show Alterations in Cancer Cells, Tumor Biomarkers Can Be Measured in Blood Samples, Knowledge of Mechanisms Involved in Carcinogenesis Has Led to the Development of New Therapies, There Are Many Immunologic Aspects of Cancer, Summary, References, Useful Web Sites, Glossary.
Topics Discussed: cancer.
Excerpt:"After studying this chapter, you should be able to:..."
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