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Jawetz, Melnick, & Adelberg's Medical Microbiology, 25e
| Section I. Fundamentals of Microbiology > |
Chapter 7. Microbial Genetics
Sections: Microbial Genetics: Introduction, Organization of Genes, Replication, Transfer of DNA, Mutation & Gene Rearrangement, Gene Expression, Genetic Engineering, Characterization of Cloned DNA, Site-Directed Mutagenesis, Analysis with Cloned DNA: Hybridization Probes, Manipulation of Cloned DNA, References.
Topics Discussed: genetics, microbial.
Excerpt:"The science of genetics defines and analyzes heredity, or constancy and change in the vast array of physiologic functions that form the properties of organisms. The basic unit of heredity is the gene, a segment of deoxyribonucleic acid (DNA) that encodes in its nucleotide sequence information for a specific physiologic property. The traditional approach to genetics has been to identify genes on the basis of their contribution to phenotype, or the collective structural and physiologic properties of an organism. A phenotypic property, be it eye color in humans or resistance to antibiotics in a bacterium, is generally observed at the level of the organism. The chemical basis for variation in phenotype is change in genotype, or alteration in the DNA sequence, within a gene or within the organization of genes...."
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