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Quick Medical Diagnosis & Treatment
Rhesus Alloimmunization, Prevention of
Sections: Key Features, Clinical Findings, Diagnosis, Treatment.
Topics Discussed: hemolytic disease of fetus or newborn due to rhd isoimmunization.
Excerpt: | |  Anti-Rho(D) antibody is responsible for most severe instances
Occurs when a Rho(D)-negative woman carries a Rho(D)-positive fetus and develops antibodies against Rho(D) The antibody developed against Rho(D) persists and poses a threat of hemolytic disease in subsequent Rho(D)-positive fetuses Passive immunization of Rho(D)-negative mothers after delivery destroys fetal Rho(D)-positive cells and prevents formation of antibodies, which would cause disease in subsequent Rho(D)-positive gestations |
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