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Quick Medical Diagnosis & Treatment Medullary Sponge Kidney Sections: Key Features, Clinical Findings, Diagnosis, Treatment. Excerpt: | | A relatively common and benign disorder
Present at birth and not usually diagnosed until the fourth or fifth decade
Caused by autosomal dominant mutations in the MCKD1 or MCKD2 genes on chromosomes 1 and 16, respectively
Kidneys have a marked irregular enlargement of the medullary and interpapillary collecting ducts
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