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Harrison's Principles of Internal Medicine, 18e | Part 8. Infectious Diseases > Section 2. Clinical Syndromes. Community-Acquired Infections > | Chapter e23. Infectious Complications of Burns Sections: Infectious Complications of Burns: Introduction, Epidemiology, Pathophysiology, Clinical Manifestations, Treatment: Burn Wound Infections, Further Readings. Topics Discussed: burn infection; burns; skin and soft-tissue infections. Excerpt:"The skin is an essential component of the nonspecific immune system, protecting the host from potential pathogens in the environment. Breaches in this protective barrier thus represent a form of immunocompromise that predisposes a patient to infection. Thermal burns may cause massive destruction of the integument as well as derangements in humoral and cellular immunity, permitting the development of infection caused by environmental opportunists and components of the host's skin flora...."
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