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Harrison's Principles of Internal Medicine, 18e | Part 8. Infectious Diseases > Section 3. Clinical Syndromes. Health Care–Associated Infections > | Chapter 131. Health CareAssociated Infections Sections: Health CareAssociated Infections: Introduction, Organization, Responsibilities, and Increasing Scrutiny of Health CareAssociated Infections, Surveillance, Epidemiologic Basis and General Measures for Prevention and Control, Nosocomial and Device-Related Infections, Isolation Techniques, Epidemic and Emerging Problems, Employee Health Service Issues, Further Readings. Topics Discussed: nosocomial infection. Excerpt:"The costs of hospital-acquired (nosocomial) and other health careassociated infections are great. It is estimated that these infections affect 1.7 million patients, cost $2833 billion, and contribute to 99,000 deaths in U.S. hospitals annually. Although efforts to lower infection risks have been challenged by the growing numbers of immunocompromised patients, antibiotic-resistant bacteria, fungal and viral superinfections, and invasive devices and procedures, the viewpoint of consumer advocatesoften termed "zero tolerance"is that almost all health careassociated infections should be avoidable with strict application of evidence-based guidelines for prevention and control (Table 131-1). This chapter reviews health careacquired and device-related infections as well as basic surveillance, prevention, control, and treatment activities...."
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