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Harrison's Principles of Internal Medicine, 18e
| Part 1. Introduction to Clinical Medicine > |
Chapter 1. The Practice of Medicine
Sections: The Modern-Day Physician, Clinical Skills, Principles of Patient Care, The Patient-Physician Relationship, The Twenty-First-Century Physician: Expanding Frontiers, Further Readings.
Topics Discussed: clinical medicine.
Excerpt:"The practice of medicine has changed in significant ways since the first edition of this book appeared more than 60 years ago. The advent of molecular genetics, molecular biology, and molecular pathophysiology, sophisticated new imaging techniques, and advances in bioinformatics and information technology have contributed to an explosion of scientific information that has fundamentally changed the way physicians define, diagnose, treat, and prevent disease. This growth of scientific knowledge is ongoing and accelerating.Deductive reasoning and applied technology form the foundation for the solution to many clinical problems. Spectacular advances in biochemistry, cell biology, and genomics, coupled with newly developed imaging techniques, allow access to the innermost parts of the cell and provide a window to the most remote recesses of the body. Revelations about the nature of genes and single cells have opened the portal for formulating a new molecular basis for the physiology of systems. Increasingly, physicians are learning how subtle changes in many different genes can affect the function of cells and organisms. Researchers are beginning to decipher the complex mechanisms by which genes are regulated. Doctors have developed a new appreciation of the role of..."
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