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Harrison's Principles of Internal Medicine, 18e | Part 2. Cardinal Manifestations and Presentation of Diseases > Section 4. Disorders of Eyes, Ears, Nose, and Throat > | Chapter 31. Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Tract Infections Sections: Pharyngitis, Sinusitis, Otitis, and Other Upper Respiratory Tract Infections: Introduction, Nonspecific Infections of the Upper Respiratory Tract, Infections of the Sinus, Infections of the Ear and Mastoid, Infections of the Pharynx and Oral Cavity, Infections of the Larynx and Epiglottis, Infections of the Deep Neck Structures, Further Readings. Topics Discussed: respiratory tract infections, upper. Excerpt:"Infections of the upper respiratory tract (URIs) have a tremendous impact on public health. They are among the most common reasons for visits to primary care providers, and although the illnesses are typically mild, their high incidence and transmission rates place them among the leading causes of time lost from work or school. Even though a minority (~25%) of cases are caused by bacteria, URIs are the leading diagnoses for which antibiotics are prescribed on an outpatient basis in the United States. The enormous consumption of antibiotics for these illnesses has contributed to the rise in antibiotic resistance among common community-acquired pathogens such as Streptococcus pneumoniaea trend that in itself has had an enormous influence on public health...."
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