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Harrison's Principles of Internal Medicine, 18e
| Part 2. Cardinal Manifestations and Presentation of Diseases > Section 9. Alterations in the Skin > |
Chapter 54. Immunologically Mediated Skin Diseases
Sections: Immunologically Mediated Skin Diseases: Introduction, Autoimmune Cutaneous Diseases, Autoimmune Systemic Diseases with Prominent Cutaneous Features, Further Readings.
Topics Discussed: dermatologic disorders; systemic lupus erythematosus and other collagen-vascular diseases.
Excerpt:"A number of immunologically mediated skin diseases and immunologically mediated systemic disorders with cutaneous manifestations are now recognized as distinct entities with consistent clinical, histologic, and immunopathologic findings. Clinically, these disorders are characterized by morbidity (pain, pruritus, disfigurement) and, in some instances, by mortality (largely due to loss of epidermal barrier function and/or secondary infection). The major features of the more common immunologically mediated skin diseases are summarized in this chapter (Table 54-1) as are the systemic disorders with cutaneous manifestations...."
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