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Harrison's Principles of Internal Medicine, 18e
| Part 8. Infectious Diseases > Section 10. Diseases Caused by Rickettsiae, Mycoplasmas, and Chlamydiae > |
Chapter 174. Rickettsial Diseases
Sections: Rickettsial Diseases: Introduction, Tick-, Mite-, Louse-, and Flea-Borne Rickettsioses, Scrub Typhus, Ehrlichioses and Anaplasmosis, Q Fever, Acknowledgment, Further Readings.
Topics Discussed: rickettsia; rickettsia infections.
Excerpt:"The rickettsiae are a heterogeneous group of small, obligately intracellular, gram-negative coccobacilli and short bacilli, most of which are transmitted by a tick, mite, flea, or louse vector. Except in the case of louse-borne typhus, humans are incidental hosts. Among rickettsiae, Coxiella burnetii, Rickettsia prowazekii, and R. typhi have the well-documented ability to survive for an extended period outside the reservoir or vector and to be extremely infectious: inhalation of a single Coxiella microorganism can cause pneumonia. High infectivity and severe illness after inhalation make R. prowazekii, R. rickettsii, R. typhi, R. conorii, and C. burnetii bioterrorism threats...."
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