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Harrison's Principles of Internal Medicine, 18e | Part 10. Disorders of the Cardiovascular System > Section 1. Introduction to Cardiovascular Disorders > | Chapter 226. Approach to the Patient with Possible Cardiovascular Disease Sections: The Magnitude of the Problem, Cardiac Symptoms, Pitfalls in Cardiovascular Medicine, Acknowledgment, Further Readings. Topics Discussed: cardiovascular disorders; cardiovascular examination and evaluation. Excerpt:"Cardiovascular diseases comprise the most prevalent serious disorders in industrialized nations and are a rapidly growing problem in developing nations (Chap. 225). Age-adjusted death rates for coronary heart disease have declined by two-thirds in the last 4 decades in the United States, reflecting the identification and reduction of risk factors as well as improved treatments and interventions for the management of coronary artery disease, arrhythmias, and heart failure. Nonetheless, cardiovascular diseases remain the most common causes of death, responsible for 35% of all deaths, almost 1 million deaths each year. Approximately one-fourth of these deaths are sudden. In addition, cardiovascular diseases are highly prevalent, diagnosed in 80 million adults, or ~35% of the adult population. The growing prevalence of obesity (Chap. 77), type 2 diabetes mellitus (Chap. 344), and metabolic syndrome (Chap. 242), which are important risk factors for atherosclerosis, now threatens to reverse the progress that has been made in the age-adjusted reduction in the mortality rate of coronary heart disease...."
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