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Harrison's Principles of Internal Medicine, 18e | Part 8. Infectious Diseases > Section 16. Fungal Infections > | Chapter 202. Cryptococcosis Sections: Cryptococcosis: Introduction, Prognosis and Complications, Further Readings. Topics Discussed: cryptococcosis; fungal infections, invasive. Excerpt:"Cryptococcus, a genus of yeast-like fungi, is the etiologic agent of cryptococcosis. There are two species, C. neoformans and C. gattii, each of which can cause cryptococcosis in humans. C. neoformans occurs in two varieties known as grubii and neoformans, which correlate with serotypes A and D, respectively. C. gattii has not been divided into varieties but is also antigenically diverse, consisting of serotypes B and C. Most clinical microbiology laboratories do not routinely distinguish between C. neoformans and C. gattii or among varieties, but rather identify and report all isolates simply as C. neoformans...."
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