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Harrison's Principles of Internal Medicine, 18e
| Part 8. Infectious Diseases > Section 17. Protozoal and Helminthic Infections: General Considerations > |
Chapter 208. Agents Used to Treat Parasitic Infections
Sections: Agents Used to Treat Parasitic Infections: Introduction, Further Readings.
Topics Discussed: antiparasitic agents; parasites; parasitic diseases; parasitology; therapy of parasitic infections.
Excerpt:"Parasitic infections afflict more than half of the world's population and impose a substantial health burden, particularly in underdeveloped nations, where they are most prevalent. The reach of some parasitic diseases, including malaria, has expanded over the past few decades as a result of factors such as deforestation, population shifts, global warming, and other climatic events. Despite major efforts at vaccine development and vector control, chemotherapy remains the single most effective means of controlling parasitic infections. Efforts to combat the spread of some diseases are hindered by the development and spread of drug resistance, the limited introduction of new antiparasitic agents, and the proliferation of counterfeit medications. However, there are good reasons to be optimistic. The past 10 years have witnessed the launch of ambitious global initiatives aimed at controlling or eliminating threats such as AIDS, tuberculosis, and malaria. Recognition of the substantial burden imposed by the "neglected" tropical diseases has generated multinational partnerships to develop and deploy effective antiparasitic agents. Vaccines against several tropical diseases are being developed, and clinical trials have begun for vaccines against schistosomiasis, hookworm, and leishmaniasis..."
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