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Harrison's Principles of Internal Medicine, 18e | Part 2. Cardinal Manifestations and Presentation of Diseases > Section 10. Hematologic Alterations > | Chapter 60. Disorders of Granulocytes and Monocytes Sections: Disorders of Granulocytes and Monocytes: Introduction, Neutrophils, Mononuclear Phagocytes, Eosinophils, Hyperimmunoglobulin ERecurrent Infection Syndrome, Laboratory Diagnosis and Management, Further Readings. Topics Discussed: granulocyte; monocyte; pathophysiology of blood disorders; pathophysiology of disorders of the immune system; red and white blood cells. Excerpt:"Leukocytes, the major cells comprising inflammatory and immune responses, include neutrophils, T and B lymphocytes, natural killer (NK) cells, monocytes, eosinophils, and basophils. These cells have specific functions, such as antibody production by B lymphocytes or destruction of bacteria by neutrophils, but in no single infectious disease is the exact role of the cell types completely established. Thus, whereas neutrophils are classically thought to be critical to host defense against bacteria, they may also play important roles in defense against viral infections...."
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