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Harrison's Principles of Internal Medicine, 18e | Part 7. Oncology and Hematology > Section 1. Neoplastic Disorders > | Chapter 86. Infections in Patients with Cancer Sections: Infections in Patients with Cancer: Introduction, System-Specific Syndromes, Abnormalities that Predispose to Infection, Prevention of Infection in Cancer Patients, Further Readings. Topics Discussed: cancer infection complication; immunocompromised host, infection in; infectious disease pathology; pharmacotherapy of infectious diseases; therapy of microbial diseases; bacterial, viral, fungal, and protozoal infections. Excerpt:"Infections are a common cause of death and an even more common cause of morbidity in patients with a wide variety of neoplasms. Autopsy studies show that most deaths from acute leukemia and half of deaths from lymphoma are caused directly by infection. With more intensive chemotherapy, patients with solid tumors have also become more likely to die of infection. Fortunately, an evolving approach to prevention and treatment of infectious complications of cancer has decreased infection-associated mortality rates and will probably continue to do so. This accomplishment has resulted from three major steps:..."
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