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Harrison's Principles of Internal Medicine, 18e
| Part 7. Oncology and Hematology > Section 1. Neoplastic Disorders > |
Chapter 98. Soft Tissue and Bone Sarcomas and Bone Metastases
Sections: Soft Tissue and Bone Sarcomas and Bone Metastases: Introduction, Soft Tissue Sarcomas, Bone Sarcomas, Tumors Metastatic to Bone, Further Readings.
Topics Discussed: pathophysiology of neoplasia.
Excerpt:"Sarcomas are rare (<1% of all malignancies) mesenchymal neoplasms that arise in bone and soft tissues. These tumors are usually of mesodermal origin, although a few are derived from neuroectoderm, and they are biologically distinct from the more common epithelial malignancies. Sarcomas affect all age groups; 15% are found in children <15 years of age, and 40% occur after age 55 years. Sarcomas are one of the most common solid tumors of childhood and are the fifth most common cause of cancer deaths in children. Sarcomas may be divided into two groups, those derived from bone and those derived from soft tissues...."
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