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Harrison's Principles of Internal Medicine, 18e | Part 7. Oncology and Hematology > Section 2. Hematopoietic Disorders > | Chapter 103. Iron Deficiency and Other Hypoproliferative Anemias Sections: Iron Deficiency and Other Hypoproliferative Anemias: Introduction, Iron Metabolism, Iron-Deficiency Anemia, Other Hypoproliferative Anemias, Further Readings. Topics Discussed: anemias; iron deficiency anemia; pathophysiology of blood disorders; red and white blood cells. Excerpt:"Anemias associated with normocytic and normochromic red cells and an inappropriately low reticulocyte response (reticulocyte index <22.5) are hypoproliferative anemias. This category includes early iron deficiency (before hypochromic microcytic red cells develop), acute and chronic inflammation (including many malignancies), renal disease, hypometabolic states such as protein malnutrition and endocrine deficiencies, and anemias from marrow damage...."
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