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Harrison's Principles of Internal Medicine, 18e | Part 7. Oncology and Hematology > Section 2. Hematopoietic Disorders > | Chapter 109. Acute and Chronic Myeloid Leukemia Sections: Acute and Chronic Myeloid Leukemia: Introduction, Acute Myeloid Leukemia, Chronic Myeloid Leukemia, Further Readings. Topics Discussed: leukemia, acute; leukemia, chronic; pathophysiology of blood disorders; pathophysiology of neoplasia; toxic responses of the blood. Excerpt:"The myeloid leukemias are a heterogeneous group of diseases characterized by infiltration of the blood, bone marrow, and other tissues by neoplastic cells of the hematopoietic system. In 2010 the estimated number of new myeloid leukemia cases in the United States was 17,200. These leukemias comprise a spectrum of malignancies that, untreated, range from rapidly fatal to slowly growing. Based on their untreated course, the myeloid leukemias have traditionally been designated acute or chronic...."
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