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Harrison's Principles of Internal Medicine, 18e | Part 8. Infectious Diseases > Section 2. Clinical Syndromes. Community-Acquired Infections > | Chapter 128. Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning Sections: Acute Infectious Diarrheal Diseases and Bacterial Food Poisoning: Introduction, Pathogenic Mechanisms, Host Defenses, Epidemiology, Laboratory Evaluation, Prophylaxis, Acknowledgments, Further Readings. Topics Discussed: diarrhea, constipation, and irritable bowel syndrome; diarrhea, infectious; food poisoning, bacterial; gastrointestinal infections and enterotoxigenic poisonings. Excerpt:"Ranging from a mild annoyance to a devastating dehydrating illness, acute diarrheal disease is a leading cause of illness globally, with an estimated 4.6 billion episodes worldwide per year. Diarrheal disease ranks second only to lower respiratory infection as the most common infectious cause of death worldwide. Among children <5 years old, diarrheal disease is a particularly important cause of death. Every year nearly 2 million children in this age group die of diarrheal disease; the majority of these young children are impoverished and live in resource-poor areas. By contributing to malnutrition and thereby reducing resistance to other infectious agents, diarrheal disease is also an indirect factor in a far greater burden of disease...."
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