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Harrison's Principles of Internal Medicine, 18e | Part 8. Infectious Diseases > Section 5. Diseases Caused by Gram-Positive Bacteria > | Chapter 135. Staphylococcal Infections Sections: Staphylococcal Infections: Introduction, Microbiology and Taxonomy, S. Aureus Infections, Coagulase-Negative Staphylococcal Infections, Further Readings. Topics Discussed: staphylococcal infections. Excerpt:"Staphylococcus aureus, the most virulent of the many staphylococcal species, has demonstrated its versatility by remaining a major cause of morbidity and mortality despite the availability of numerous effective antistaphylococcal antibiotics. S. aureus is a pluripotent pathogen, causing disease through both toxin-mediated and non-toxin-mediated mechanisms. This organism is responsible for both nosocomial and community-based infections that range from relatively minor skin and soft tissue infections primarily to life-threatening systemic infections...."
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