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Harrison's Principles of Internal Medicine, 18e
| Part 8. Infectious Diseases > Section 8. Mycobacterial Diseases > |
Chapter 165. Tuberculosis
Sections: Tuberculosis: Introduction, Etiologic Agent, Epidemiology, Pathogenesis and Immunity, Clinical Manifestations, Diagnosis, Prevention, Principles of TB Control, Further Readings.
Topics Discussed: tuberculosis.
Excerpt:"Tuberculosis (TB), which is one of the oldest diseases known to affect humans and is likely to have existed in prehominids, is a major cause of death worldwide. This disease is caused by bacteria of the Mycobacterium tuberculosis complex and usually affects the lungs, although other organs are involved in up to one-third of cases. If properly treated, TB caused by drug-susceptible strains is curable in virtually all cases. If untreated, the disease may be fatal within 5 years in 50–65% of cases. Transmission usually takes place through the airborne spread of droplet nuclei produced by patients with infectious pulmonary TB...."
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