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Harrison's Principles of Internal Medicine, 18e
| Part 10. Disorders of the Cardiovascular System > Section 4. Disorders of the Heart > |
Chapter 238. Cardiomyopathy and Myocarditis
Sections: Definition and Classification, General Presentation, Genetic Etiologies of Cardiomyopathy, Dilated Cardiomyopathy, Overlap between Cardiomyopathies, Restrictive Cardiomyopathy, Hypertrophic Cardiomyopathy, Further Readings.
Topics Discussed: cardiomyopathy; diastolic heart failure and the cardiomyopathies; myocarditis.
Excerpt:"Cardiomyopathy is disease of the heart muscle. It is estimated that cardiomyopathy accounts for 5–10% of the 5–6 million patients already diagnosed with heart failure in the United States. This term is intended to exclude cardiac dysfunction that results from other structural heart disease, such as coronary artery disease, primary valve disease, or severe hypertension; however, in general usage the phrase ischemic cardiomyopathy is sometimes applied to describe diffuse dysfunction occurring in the presence of multivessel coronary artery disease, and nonischemic cardiomyopathy to describe cardiomyopathy from other causes. As of 2006, cardiomyopathies are defined as "a heterogeneous group of diseases of the myocardium associated with mechanical and/or electrical dysfunction that usually (but not invariably) exhibit inappropriate ventricular hypertrophy or dilatation and are due to a variety of causes that frequently are genetic."..."
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