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Harrison's Principles of Internal Medicine, 18e
| Part 11. Disorders of the Respiratory System > Section 2. Diseases of the Respiratory System > |
Chapter 254. Asthma
Sections: Asthma: Introduction, Prevalence, Etiology, Pathogenesis, Asthma Triggers, Pathophysiology, Clinical Features and Diagnosis, Acute Severe Asthma, Refractory Asthma, Special Considerations, Further Readings.
Topics Discussed: asthma.
Excerpt:"Asthma is a syndrome characterized by airflow obstruction that varies markedly, both spontaneously and with treatment. Asthmatics harbor a special type of inflammation in the airways that makes them more responsive than nonasthmatics to a wide range of triggers, leading to excessive narrowing with consequent reduced airflow and symptomatic wheezing and dyspnea. Narrowing of the airways is usually reversible, but in some patients with chronic asthma there may be an element of irreversible airflow obstruction. The increasing global prevalence of asthma, the large burden it now imposes on patients, and the high health care costs have led to extensive research into its mechanisms and treatment...."
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