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Harrison's Principles of Internal Medicine, 18e
| Part 11. Disorders of the Respiratory System > Section 2. Diseases of the Respiratory System > |
Chapter 260. Chronic Obstructive Pulmonary Disease
Sections: Chronic Obstructive Pulmonary Disease: Introduction, Risk Factors, Natural History, Pathophysiology, Pathology, Pathogenesis, Clinical Presentation, Further Readings.
Topics Discussed: chronic obstructive pulmonary disease.
Excerpt:"Chronic obstructive pulmonary disease (COPD) is defined as a disease state characterized by airflow limitation that is not fully reversible (http://www.goldcopd.com/). COPD includes emphysema, an anatomically defined condition characterized by destruction and enlargement of the lung alveoli; chronic bronchitis, a clinically defined condition with chronic cough and phlegm; and small airways disease, a condition in which small bronchioles are narrowed. COPD is present only if chronic airflow obstruction occurs; chronic bronchitis without chronic airflow obstruction is not included within COPD...."
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