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Harrison's Principles of Internal Medicine, 18e | Part 13. Disorders of the Kidney and Urinary Tract > | Chapter 285. Tubulointerstitial Diseases of the Kidney Sections: Tubulointerstitial Diseases of the Kidney: Introduction, Acute Interstitial Nephritis, Chronic Tubulointerstitial Diseases, Metabolic Disorders, Global Perspective, Acknowledgment, Further Readings. Topics Discussed: nephritis, interstitial. Excerpt:"Inflammation or fibrosis of the renal interstitium and atrophy of the tubular compartment are common consequences of diseases that target the glomeruli or vasculature. Distinct from these secondary phenomena, however, are a group of disorders that primarily affect the tubules and interstitium, with relative sparing of the glomeruli and renal vessels. Such disorders are conveniently divided into acute and chronic tubulointerstitial nephritis (TIN) (Table 285-1)...."
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