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Harrison's Principles of Internal Medicine, 18e
| Part 13. Disorders of the Kidney and Urinary Tract > |
Chapter 286. Vascular Injury to the Kidney
Sections: Vascular Injury to the Kidney: Introduction, Atherosclerosis and Kidney Circulation, Atheroembolic Renal Disease, Thromboembolic Renal Disease, Microvascular Injury and Hypertension, Thrombotic Microangiopathy, Renal Vein Thrombosis, Further Readings.
Topics Discussed: renal vascular disorders.
Excerpt:"The renal vasculature is unusually complex with rich arteriolar flow to the cortex in excess of metabolic requirements, consistent with its primary function as a filtering organ. After delivering blood to cortical glomeruli, the postglomerular circulation supplies deeper medullary segments that support energy-dependent solute transport at multiple levels of the renal tubule. These postglomerular vessels carry less blood, and high oxygen consumption leaves the deeper medullary regions at the margin of hypoxemia. Vascular disorders that commonly threaten the blood supply of the kidney include large vessel atherosclerosis, fibromuscular diseases, and embolic, inflammatory, and primary hematologic disorders that produce microvascular injury...."
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