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Harrison's Principles of Internal Medicine, 18e
| Part 14. Disorders of the Gastrointestinal System > Section 1. Disorders of the Alimentary Tract > |
Chapter 300. Acute Appendicitis and Peritonitis
Sections: Acute Appendicitis, Clinical Manifestations, Acute Peritonitis, Further Readings.
Topics Discussed: appendicitis, acute; intraabdominal infections; peritonitis.
Excerpt:"With more than 250,000 appendectomies performed annually, appendicitis is the most common abdominal surgical emergency in the United States. The peak incidence of acute appendicitis is in the second and third decades of life; it is relatively rare at the extremes of age. However, perforation is more common in infancy and in the elderly, during which periods mortality rates are highest. Males and females are equally affected, except between puberty and age 25, when males predominate in a 3:2 ratio. The incidence of appendicitis has remained stable in the United States over the last 30 years, while the incidence of appendicitis is much lower in underdeveloped countries, especially parts of Africa, and in lower socioeconomic groups. The mortality rate in the United States decreased eightfold between 1941 and 1970 but has remained at <1 per 100,000 since then...."
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