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Harrison's Principles of Internal Medicine, 18e | Part 14. Disorders of the Gastrointestinal System > Section 2. Liver and Biliary Tract DiseaseĀ > | Chapter 308. Cirrhosis and Its Complications Sections: Cirrhosis and Its Complications: Introduction, Alcoholic Cirrhosis, Cirrhosis Due to Chronic Viral Hepatitis B or C, Cirrhosis from Autoimmune Hepatitis and Nonalcoholic Fatty Liver Disease, Biliary Cirrhosis, Cardiac Cirrhosis, Other Types of Cirrhosis, Major Complications of Cirrhosis, Further Readings. Topics Discussed: liver cirrhosis; portal hypertension and cirrhosis. Excerpt:"Cirrhosis is a condition that is defined histopathologically and has a variety of clinical manifestations and complications, some of which can be life-threatening. In the past, it has been thought that cirrhosis was never reversible; however, it has become apparent that when the underlying insult that has caused the cirrhosis has been removed, there can be reversal of fibrosis. This is most apparent with the successful treatment of chronic hepatitis C; however, reversal of fibrosis is also seen in patients with hemochromatosis who have been successfully treated and in patients with alcoholic liver disease who have discontinued alcohol use...."
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