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Harrison's Principles of Internal Medicine, 18e | Part 14. Disorders of the Gastrointestinal System > Section 2. Liver and Biliary Tract DiseaseĀ > | Chapter 311. Diseases of the Gallbladder and Bile Ducts Sections: Physiology of Bile Production and Flow, Diseases of the Gallbladder, Diseases of the Bile Ducts, Further Readings. Topics Discussed: biliary tract diseases; gallbladder disease. Excerpt:"Bile formed in the hepatic lobules is secreted into a complex network of canaliculi, small bile ductules, and larger bile ducts that run with lymphatics and branches of the portal vein and hepatic artery in portal tracts situated between hepatic lobules. These interlobular bile ducts coalesce to form larger septal bile ducts that join to form the right and left hepatic ducts, which in turn, unite to form the common hepatic duct. The common hepatic duct is joined by the cystic duct of the gallbladder to form the common bile duct (CBD), which enters the duodenum (often after joining the main pancreatic duct) through the ampulla of Vater...."
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