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Harrison's Principles of Internal Medicine, 18e | Part 14. Disorders of the Gastrointestinal System > Section 3. Disorders of the Pancreas > | Chapter 313. Acute and Chronic Pancreatitis Sections: Biochemistry and Physiology of Pancreatic Exocrine Secretion, Acute Pancreatitis, Chronic Pancreatitis and Pancreatic Exocrine Insufficiency, Other Conditions, Acknowledgments, Further Readings. Topics Discussed: pancreatitis; pancreatitis, acute; pancreatitis, chronic. Excerpt:"The pancreas secretes 15003000 mL of isosmotic alkaline (pH >8) fluid per day containing about 20 enzymes. The pancreatic secretions provide the enzymes needed to effect the major digestive activity of the gastrointestinal tract and provide an optimal pH for the function of these enzymes...."
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