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Harrison's Principles of Internal Medicine, 18e
| Part 15. Disorders of the Joints and Adjacent Tissues > Section 2. Disorders of Immune-Mediated Injury > |
Chapter 326. The Vasculitis Syndromes
Sections: Definition, Classification, Pathophysiology and Pathogenesis, Granulomatosis with Polyangiitis (Wegener's), Microscopic Polyangiitis, Churg-Strauss Syndrome, Polyarteritis Nodosa, Giant Cell Arteritis and Polymyalgia Rheumatica, Takayasu's Arteritis, Henoch-Schönlein Purpura, Idiopathic Cutaneous Vasculitis, Cryoglobulinemic Vasculitis, Behçet's Syndrome, Isolated Vasculitis of the Central Nervous System, Cogan's Syndrome, Kawasaki Disease, Polyangiitis Overlap Syndromes, Secondary Vasculitis, Further Readings.
Topics Discussed: vascular diseases; vasculitis.
Excerpt:"Vasculitis is a clinicopathologic process characterized by inflammation of and damage to blood vessels. The vessel lumen is usually compromised, and this is associated with ischemia of the tissues supplied by the involved vessel. A broad and heterogeneous group of syndromes may result from this process, since any type, size, and location of blood vessel may be involved. Vasculitis and its consequences may be the primary or sole manifestation of a disease; alternatively, vasculitis may be a secondary component of another primary disease. Vasculitis may be confined to a single organ, such as the skin, or it may simultaneously involve several organ systems...."
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