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Harrison's Principles of Internal Medicine, 18e
| Part 17. Neurologic Disorders > Section 2. Diseases of the Central Nervous System > |
Chapter 380. Multiple Sclerosis and Other Demyelinating Diseases
Sections: Multiple Sclerosis and Other Demyelinating Diseases: Introduction, Multiple Sclerosis, Acute Disseminated Encephalomyelitis (ADEM), Further Readings.
Topics Discussed: demyelinating disease; multiple sclerosis.
Excerpt:"Demyelinating disorders are immune-mediated conditions characterized by preferential destruction of central nervous system (CNS) myelin. The peripheral nervous system (PNS) is spared, and most patients have no evidence of an associated systemic illness. Multiple sclerosis (MS), the most common disease in this category, is second only to trauma as a cause of neurologic disability beginning in early to middle adulthood...."
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