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Harrison's Principles of Internal Medicine, 18e
| Part 17. Neurologic Disorders > Section 2. Diseases of the Central Nervous System > |
Chapter 381. Meningitis, Encephalitis, Brain Abscess, and Empyema
Sections: Meningitis, Encephalitis, Brain Abscess, and Empyema: Introduction, Approach to the Patient: Meningitis, Encephalitis, Brain Abscess, and Empyema, Acute Bacterial Meningitis, Acute Viral Meningitis, Viral Encephalitis, Subacute Meningitis, Chronic Encephalitis, Brain Abscess, Nonbacterial Causes of Infectious Focal CNS Lesions, Subdural Empyema, Cranial Epidural Abscess, Suppurative Thrombophlebitis, Further Readings.
Topics Discussed: central nervous system infection.
Excerpt:"Acute infections of the nervous system are among the most important problems in medicine because early recognition, efficient decision-making, and rapid institution of therapy can be lifesaving. These distinct clinical syndromes include acute bacterial meningitis, viral meningitis, encephalitis, focal infections such as brain abscess and subdural empyema, and infectious thrombophlebitis. Each may present with a nonspecific prodrome of fever and headache, which in a previously healthy individual may initially be thought to be benign, until (with the exception of viral meningitis) altered consciousness, focal neurologic signs, or seizures appear. Key goals of early management are to emergently distinguish between these conditions, identify the responsible pathogen, and initiate appropriate antimicrobial therapy...."
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