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Harrison's Principles of Internal Medicine, 18e
| Part 17. Neurologic Disorders > Section 6. Alcoholism and Drug Dependency > |
Chapter 394. Cocaine and Other Commonly Abused Drugs
Sections: Cocaine and Other Commonly Abused Drugs: Introduction, Cocaine, Marijuana and Cannabis Compounds, Methamphetamine, Lysergic Acid Diethylamide (LSD), Phencyclidine (PCP), Other Drugs of Abuse, Polydrug Abuse, Further Readings.
Topics Discussed: cocaine; cocaine abuse; drug abuse; illicit drugs; substance-related disorders: overview and depressants, stimulants, and hallucinogens.
Excerpt:"The abuse of cocaine and other psychostimulant drugs reflects a complex interaction between the pharmacologic properties of each drug, the personality and expectations of the user, and the environmental context in which the drug is used. Polydrug abuse involving the concurrent use of several drugs with different pharmacologic effects is increasingly common. Some forms of polydrug abuse, such as the combined use of heroin and cocaine intravenously, are especially dangerous and are a major problem in hospital emergency rooms. Sometimes one drug is used to enhance the effects of another, as with the combined use of benzodiazepines and methadone, or cocaine and heroin in methadone-maintained patients...."
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