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Harrison's Principles of Internal Medicine, 18e | Part 8. Infectious Diseases > Section 12. Infections Due to DNA Viruses > | Chapter 184. Parvovirus Infections Sections: Parvovirus Infections: Introduction, Parvovirus B19, Parv4/5, Human Bocaviruses, Further Readings. Topics Discussed: infections, parvovirus. Excerpt:"Parvoviruses, members of the family Parvoviridae, are small (diameter, 22 nm), nonenveloped, icosahedral-shaped viruses with a linear single-strand DNA genome of 5000 nucleotides. These viruses are dependent on either rapidly dividing host cells or helper viruses for replication. At least four groups of parvoviruses infect humans: parvovirus B19 (B19V), dependoviruses (adeno-associated viruses; AAVs), PARV4/5 virus, and human bocaviruses (HBoVs). Human dependoviruses are nonpathogenic and will not be considered further in this chapter...."
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