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Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e

Laurence L. Brunton, Bruce A. Chabner, Björn C. Knollmann
Editors of the online edition:
Editor-in-Chief: Laurence L. Brunton
Associate Editors: Donald K. Blumenthal, Nelda Murri, and Randa Hilal-Dandan
Consulting Editor: Björn C. Knollmann


Preface    Preface to the Online Edition    Copyright    Contributors    UPDATED 12th Edition index (PDF)

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Click on an individual Section title to collapse or expand the Section view.

 Section I. General Principles
Chapter 1Drug Invention and the Pharmaceutical Industry
Latest Update:

Grand Round:
Chapter 2Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination
Chapter 3Pharmacodynamics: Molecular Mechanisms of Drug Action
Chapter 4Drug Toxicity and Poisoning
Grand Round:
Chapter 5Membrane Transporters and Drug Response
Chapter 6Drug Metabolism
Chapter 7Pharmacogenetics
 Section II. Neuropharmacology
Chapter 8Neurotransmission: The Autonomic and Somatic Motor Nervous Systems
Chapter 9Muscarinic Receptor Agonists and Antagonists
Chapter 10Anticholinesterase Agents
Chapter 11Agents Acting at the Neuromuscular Junction and Autonomic Ganglia
Chapter 12Adrenergic Agonists and Antagonists
Chapter 135-Hydroxytryptamine (Serotonin) and Dopamine
Chapter 14Neurotransmission and the Central Nervous System
Chapter 15Drug Therapy of Depression and Anxiety Disorders
Chapter 16Pharmacotherapy of Psychosis and Mania
Chapter 17Hypnotics and Sedatives
Chapter 18Opioids, Analgesia, and Pain Management
Latest Update:
Chapter 19General Anesthetics and Therapeutic Gases
Chapter 20Local Anesthetics
Chapter 21Pharmacotherapy of the Epilepsies
Chapter 22Treatment of Central Nervous System Degenerative Disorders
Chapter 23Ethanol and Methanol
Chapter 24Drug Addiction
 Section III. Modulation of Cardiovascular Function
Chapter 25Regulation of Renal Function and Vascular Volume
Chapter 26Renin and Angiotensin
Latest Update:
Chapter 27Treatment of Myocardial Ischemia and Hypertension
Chapter 28Pharmacotherapy of Congestive Heart Failure
Chapter 29Anti-Arrhythmic Drugs
Grand Round:
Chapter 30Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs
Latest Update:
Chapter 31Drug Therapy for Hypercholesterolemia and Dyslipidemia
 Section IV. Inflammation, Immunomodulation, and Hematopoiesis
Chapter 32Histamine, Bradykinin, and Their Antagonists
Chapter 33Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor
Chapter 34Anti-inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout
Latest Update:
Chapter 35Immunosuppressants, Tolerogens, and Immunostimulants
Chapter 36Pulmonary Pharmacology
Chapter 37Hematopoietic Agents: Growth Factors, Minerals, and Vitamins
 Section V. Hormones and Hormone Antagonists
Chapter 38Introduction To Endocrinology: The Hypothalamic-Pituitary Axis
Chapter 39Thyroid and Anti-Thyroid Drugs
Chapter 40Estrogens and Progestins
Chapter 41Androgens
Chapter 42ACTH, Adrenal Steroids, and Pharmacology of the Adrenal Cortex
Chapter 43Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia
Chapter 44Agents Affecting Mineral Ion Homeostasis and Bone Turnover
Latest Update:
 Section VI. Drugs Affecting Gastrointestinal Function
Chapter 45Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease
Chapter 46Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease
Chapter 47Pharmacotherapy of Inflammatory Bowel Disease
 Section VII. Chemotherapy of Microbial Diseases
Chapter 48General Principles of Antimicrobial Therapy
Chapter 49Chemotherapy of Malaria
Chapter 50Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections
Chapter 51Chemotherapy of Helminth Infections
Chapter 52Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for UrinaryTract Infections
Chapter 53Penicillins, Cephalosporins, and Other β-Lactam Antibiotics
Chapter 54Aminoglycosides
Chapter 55Protein Synthesis Inhibitorsand Miscellaneous Antibacterial Agents
Chapter 56Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy
Chapter 57Antifungal Agents
Chapter 58Antiviral Agents (Nonretroviral)
Chapter 59Antiretroviral Agents and Treatment of HIV Infection
 Section VIII. Chemotherapy of Neoplastic Diseases
Chapter 60General Principles of Cancer Chemotherapy
Chapter 61Cytotoxic Agents
Chapter 62Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines
Chapter 63Natural Products in Cancer Chemotherapy: Hormones and Related Agents
 Section IX. Special Systems Pharmacology
Chapter 64Ocular Pharmacology
Chapter 65Dermatological Pharmacology
Chapter 66Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders
Chapter 67Environmental Toxicology: Carcinogens and Heavy Metals
 Section X. Appendices
Appendix IPrinciples of Prescription Order Writing and Patient Compliance
Appendix IIDesign and Optimization of Dosage Regimens: Pharmacokinetic Data


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Editorial Policy for Updates
The Editors of Goodman & Gilman's welcome your suggestions and submissions for inclusion of updates. If you are a pharmacologist, pharmacist, physician, or medical scientist and you would like the opportunity to contribute an update, please send an email to Editor-in-Chief Laurence Brunton at gg_updates@mhedu.com.
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Hemostasis: Antiplatelet, Anticoagulant, and Thrombolytic Drugs:  
Oral Anticoagulants
 
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Antiplatelet Drugs
 
Fibrinolytic Drugs
 
Oral Anticoagulants
 
Parenteral Anticoagulants
 
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Cardiac Electrophysiology and Pharmacology:
Anti-Arrhythmic Drugs
 
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Anti-Arrhythmic Drugs
 
Atrial Myocyte Electrophysiology
 
AV Node Electrophysiology
 
Effects of Antiarrhythmic Drugs on the Electrocardiogram
 
Sinus Node Electrophysiology
 
Ventricular Myocyte Electrophysiology
 
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Neuropharmacology:  
GABAergic Synaptic Transmission
 
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Adrenergic Neuroeffector Junction
 
Cholinergic Neuroeffector Junction
 
Dopaminergic Neuroeffector Junction
 
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